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SPCD has many variations in its presentation, from asymptomatic over metabolic crises at young age (sudden infant death syndrome, episodes of hypoglycemia, and Reye-like syndrome) to progressive cardiomyopathy [4]
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Taking into account the effects of mutations on rhodopsin receptor activity, they can be divided into two groups: a) mutations leading to an increase of receptor activity by creating constitutively active mutants (CAM)
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