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Structural basis for dual mechanism of Cas2/3 nuclease inhibition by anti-CRISPR protein AcrIF19 | Nature Communications
The existing evidence base comes from preclinical (animal) studies conducted primarily at Washington State University, where the compound was developed and patented for potential use in Alzheimer's disease
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106 In most cases of SS, symptoms usually resolve within 24 hours of stopping the drug, though in a minority of cases where the drug has active metabolites or a longer half-life, symptoms can last for longer than this
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