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[DOI] [PubMed] [Google Scholar] Noctor G, Gomez L, Vanacker H, Foyer CH
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Given the widely accepted pro-survival role of the PI3K/AKT pathway and that activation of this pathway depended on the presence of insulin in our study, it is reasonable to assume that the detrimental effects of vemurafenib and trametinib on melanoma cell viability were attenuated by insulin via the PI3K/AKT pathway
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