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Cys 531 and Cys 704 are close to the NADH binding site and thus it is probable that S-glutathionylation induces a conformational change in the N-module which diminishes NADH oxidation (Hurd et al., 2008)
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Administration of human sHASEGP to a patient suffering from head trauma can thus removal tissue hyaluronan accumulation and the water associated with it
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