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Longitudinal infusion of a complex of insulin-like growth factor-I and IGF-binding protein-3 in five preterm infants: pharmacokinetics and short-term safety | Pediatric Research
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hence, higher intracellular Zn levels may boost PARP activity, and further, Zn overload increases intracellular ROS in an NADPH oxidase-dependent way, suggesting that ROS generation may contribute to zinc-induced PARP activation (Figure 4A) [70,100,101,102,103]
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