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Furthermore, single-cell multiomic and barcode-based lineage tracing analyses have shown that even transcriptomically and epigenomically homogeneous starting hESC-derived DA progenitors can give rise to heterogeneous grafts after terminal differentiation in vivo in PD models (Tiklová et al., 2020
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Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP
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