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SAM subsequently donates a methyl group in various methylation reactions, becoming S-adenosylhomocysteine (SAH), which is then hydrolyzed to homocysteine by S-adenosylhomocysteine hydrolase

n acetyl cistine

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At the metabolic level, Tregs degrade ATP into immunosuppressive adenosine by highly expressing CD39, preferentially uptake glucose and tryptophan, deprive effector T cells of energy sources, and deplete their function [184]