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Two inherited diseases in the carnitine biosynthetic pathway have been reported (deficiency of 6- N -trimethyllysine dioxygenase and deficiency of γ-butyrobetaine dioxygenase), which result in only mildly decreased to normal carnitine levels in the affected patients [60, 61]

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In fact, this paper was the first of its kind to present findings from the first global modelling intercomparison initiative of global gridded crop models, focusing specifically on how state-of-the-art models represented CO2 effects on crop yield and evapotranspiration, highlighting these effects as a dominant source of uncertainty in the results, outpassing the uncertainty resulting from the use of different climate change projections

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