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Compound X a compound of formula I Aerosol mg/can Compound X 20.0 Oleic acid 10.0 Trichloromonofluoromethane 5,000.0 Dichlorodifluoromethane 10,000.0 Dichlorotetrafluoroethane 5,000.0 Inactive Ingredients % (w/w) Water 64.90 Hexadecan-1-ol (C 16 H 34 O,Cetyl alcohol) 3.0 Octadecan-1-ol (C 18 H 38 O, Stearyl alcohol) 8.5 Isopropyl myristate (C 17 H 34 O 2 ) 1.0 Glycerine 0.2 Propylene glycol 20.0 Polysorbate 20 (TWEEN 20) 2.0 Isopropyl palmitate 0.2 Benzoic Acid 0.2 Total for inactive ingredients 100.00 the above formulations may be obtained by conventional procedures well known in the pharmaceutical art

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What’s more, the NOD-like receptor family pyrin domain-containing 3 (NLRP3), also upregulated by the activation of NF-κB, 38 forms inflammasome and activates protein kinase C epsilon (PKCε), 39 thus imparting IRS-1 40 (Fig