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glutathione s-transferase uniprot and MRP1 form an integrated system involved in the storage and transport of dinitrosyl–dithiolato iron complexes in cells transferase enzyme
Glutathione-depleting Liposome Adjuvant for Augmenting the Efficacy of a Glutathione Covalent Inhibitor Oridonin for Acute Myeloid Leukemia Therapy | Journal of Nanobiotechnology | Springer Nature Link
Moreover, the other inflammatory cytokines like adhesion molecules would result in vascular dysfunction and consequently neuropathic pain (13)
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Most importantly, co-administration of nimbolide with metformin or the chemotherapeutic drugs tamoxifen/cisplatin was found to be more efficacious than single agents in abrogating IGF-1/PI3K/Akt/AR signaling suggesting that AKR inhibitors show promise in chemosensitization [199]
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