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Isoloquiritigenin led to apoptosis and autophagy-mediated cell death by decreasing cyclin D1 expression as increasing the number of cells in the sub-G1 phase, which inhibited the proliferation of breast cancer cells (141)

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Most notably, CGA protects against Aβ-induced pathology concomitant with AD in mouse models by upregulating the mRNA expression of the glycolytic enzyme phosphoglycerate kinase-1, increasing ATP production [74]